Home » Faculty » Amal Kanti Bera

Amal Kanti Bera

Amal
Associate Professor
Ph. D., University of Delhi
M. Sc., University of Calcutta
Office: BT 301
Tel: +91-44-2257-4121
Email: amal@iitm·ac·in
Lab: BT 315 (Website)

Research Areas

  • Structure function relationship of ion channels
  • Gap Junction Channel
  • GABAA Receptor Channel
  • Voltage Dependent Anion Channel of Mitochondria
  • Potassium Channel and Acid Sensing Ion Channel
  • Neuronal diseases associated with ion channels and receptors malfunctioning

Publications

  • Sahu G, Sukumaran S, Bera AK (2014) Pannexins form gap junctions with electrophysiological and pharmacological properties distinct from connexins.Sci Rep 4:4955
  • Allu PKR, Chirasani VR, Ghosh D, Mani A, Bera AK, et al. (2014) Naturally occurring variants of the dysglycemic peptide pancreastatin: differential potencies for multiple cellular functions and structure-function correlation. J Biol Chem 289 (7):4455-4469.
  • Sahu G and Bera AK (2013) Contribution of intracellular calcium and pH in ischemic uncoupling of cardiac gap junction channels formed of connexins 43, 40, and 45: a critical function of C-terminal domain. PLOS ONE 8(3):e60506.
  • Swain SM and Bera AK (2013) Coupling of proton binding in extracellular domain to channel gating in Acid Sensing Ion Channel. J Mol Neurosci 51(1):199-207.
  • Sahu BS, Obbineni JM, Sahu G, Allu PKR,SubramanianL, Sonawane PJ, Singh PK, Sasi BK, SenapatiS, Maji SK,Bera AK,et al. (2012) Functional Genetic Variants of the Catecholamine-Release-Inhibitory Peptide Catestatin in an Indian Population. J Biol Chem 287(52):43840-43852.
  • Swain SM, Parameswaran S, Sahu G, Verma RS and Bera AK (2012) Proton-gated ion channels in mouse bone marrow stromal cells. Stem Cell Res 9, 59-68.
  • Sahu BS, Obbineni JM, Sahu G, Singh P, Sonawane P, Sasi B, Allu PKR, Maji S, Bera AK, et al.(2012) Molecular interactions of the physiological anti-hypertensive peptide catestatin with the neuronal nicotinic acetylcholine receptor. J Cell Sci 125, 2323-2337.
  • Poornima V, Madhupriya M, Kootar S, Sujatha G, Kumar A and Bera AK (2012) P2X7 receptor-pannexin 1 hemichannel association: effect of extracellular calcium on membrane permeabilization. J Mol Neurosci 46, 585-594.
  • Chandrasekhar A and Bera AK (2012) Hemichannels: permeants and their effect on development, physiology and death. Cell Biochem Funct30, 89-100.
  • Mohan H, Maheswari U, BeraAK andSuraishkumar, GK (2010) Reactive oxygen species mediated modifications in Bacillus subtilis lipid membrane to improve protein productivities.Process Biochemistry45,467-474.
  • Jetti SK, Swain SM, Majumder S, Chatterjee S, Poornima V and Bera AK (2010) Evaluation of the role of nitric oxide in acid sensing ion channel mediated cell death.       Nitric Oxide 22, 213-219.
  • Allu PKR, Chirasani VR, Ghosh D, Mani A, Bera A.K.,et al. (2014) Naturally occurring variants of the dysglycemic peptide pancreastatin: differential potencies for multiple cellular functions and structure-function correlation.J Biol Chem 289 (7):4455-4469.Impact factor: 4.65; citation:
  • Sahu G and Bera, A.K., (2013) Contribution of intracellular calcium and pH in ischemic uncoupling of cardiac gap junction channels formed of connexins 43, 40, and 45: a critical function of C-terminal domain.PLOS ONE 8(3):e60506.Impact factor: 3.73; citation:
  • Swain SM and Bera, A.K.(2013) Coupling of proton binding in extracellular domain to channel gating in Acid Sensing Ion Channel.J Mol Neurosci51(1):199-207. Impact factor: 2.9; citation:1
  • Sahu BS, Obbineni JM, Sahu G, Allu PKR, Subramanian L, Sonawane PJ, Singh PK, Sasi BK, Senapati S,Maji SK, and Bera  A.K.,et al. (2012) Functional Genetic Variants of the Catecholamine-Release-Inhibitory Peptide Catestatin in an Indian Population.J Biol Chem 287(52):43840-43852.Impact factor: 4.65; citation:1
  • Swain SM, Parameswaran S, Sahu G, Verma RS and Bera A.K. (2012) Proton-gated ion channels in mouse bone marrow stromal cells.Stem Cell Res Res 9, 59-68. Impact factor: 4.46; citation:3.
  • Sahu BS, Obbineni JM, Sahu G, Singh P, Sonawane P, Sasi B, Allu PKR, Maji S, Bera AK@, et al.(2012) Molecular interactions of the physiological anti-hypertensive peptide catestatin with the neuronal nicotinic acetylcholine receptor.J Cell Sci 125, 2323-2337. @ co-corresponding author.Impact factor: 5.87; citation:7
  • Poornima V, Madhupriya M, Kootar S, Sujatha G, Kumar A and Bera A.K. (2012) P2X7 receptor-pannexin 1 hemichannel association: effect of extracellular calcium on membrane permeabilization.J Mol Neurosci 46, 585-594.Impact factor: 2.9; citation:
  • Chandrasekhar A and Bera A.K., (2012) Hemichannels: permeants and their effect on development, physiology and death.Cell Biochem Funct30, 89-100.Impact factor: 1.85; citation:12
  • Mohan H, Maheswari U, Bera A.K. and Suraishkumar, GK (2010) Reactive oxygen species mediated modifications in Bacillus subtilis lipid membrane to improve protein productivities.Process Biochemistry45,467-474.Impact factor:2.9; citation:2
  • Jetti SK, Swain SM, Majumder S, Chatterjee S, Poornima V and Bera A.K., (2010) Evaluation of the role of nitric oxide in acid sensing ion channel mediated cell death.Nitric Oxide22, 213-219. Impact factor: 3.26; citation:14
  • Before 2010

  • Bera A.K. and Akabas MH (2005) Spontaneous thermal motion of the GABAA receptor M2 channel-lining segments.J Biol Chem280, 35506-35512. Impact factor: 4.65; citation: 15
  • Bera  A.K., Chatav M. and Akabas M.H. 2002. GABAA Receptor M2-M3 Loop Secondary Structure and Changes in Accessibility During Channel Gating. J. Biol. Chem. 277(45) 43002-43010. Impact factor: 15.28; citation: 72
  • Luo X, Popov S, Bera  A.K. Wilkie TM and Muallem S (2001) RGS proteins provide biochemical control of agonist-evoked [Ca2+]i oscillations.Molecular Cell7, 651-660. Impact factor: 15.28; citation: 72
  • Keren-Raifman T, Bera  A.K., Zveig D, Peleg S, Witherow DS, Slepak VZ and Dascal N (2001) Expression levels of RGS7 and RGS4 proteins determine the mode of regulation of the G protein-activated K+ channel and control regulation of RGS7 by G beta 5. FEBS Lett492, 20-28. Impact factor: 3.58; citation:22
  • Ghosh S and Bera A.K.(2001) The role of H+ concentration on the capacitance of a membrane channel protein. J Theor Biol 208, 383-384. Impact factor: 2.35; citation:7
  • Bera A.K. and Ghosh S (2001) Dual mode of gating of voltage-dependent anion channel as revealed by phosphorylation. J Struct Biol135, 67-72.Impact factor: 3.36; citation: 31
  • Shin, D. M., Zhao, X. S., Luo, X.,Bera A.K.and Muallem, S. (2000) Specificity of Ca2+ signaling in polarized cells.Adv Dent Res 14, 12-15.Impact factor: citation: 1
  • Mullner C, Vorobiov D, Bera A.K., Uezono Y, Yakubovich D, Frohnwieser-Steinecker B, Dascal N and Schreibmayer W (2000) Heterologous facilitation of G protein-activated K+ channels by beta-adrenergic stimulation via cAMP-dependent protein kinase. J Gen Physiol, 115, 547-558. Impact factor: 4.73; citation: 54
  • Vorobiov D, Bera A.K., Keren-Raifman T, Barzilai R and Dascal N (2000) Coupling of the muscarinic m2 receptor to G protein-activated K(+) channels via Galpha(z) and a receptor-Galpha(z) fusion protein. Fusion between the receptor and Galpha(z) eliminates catalytic (collision) coupling. J Biol Chem, 275,4166-4170.Impact factor: 4.65; citation: 38
  • Ghosh S, Bera A.K. and Das S (1999) Evidence for nonlinear capacitance in biomembrane channel system. J Theor Biol200, 299-305. Impact factor: 2.35; citation:8
  • Vijayvergiya V, Ghosh P, Bera A.K. and Das S (1999) Bis[(benzo-15-crown-5)-15-yl methyl] pimelate forms ion channels in planar lipid bilayer: a novel model ion channel. Physiol Chem Phys Med NMR,31, 93-102. Impact factor: citation:3
  • Chandra A, Ghosh P, Mandaokar AD, Bera A.K.Sharma RP, Das S and Kumar PA (1999) Amino acid substitution in alpha-helix 7 of Cry1Ac delta-endotoxin of Bacillus thuringiensis leads to enhanced toxicity to Helicoverpa armigera Hubner.FEBS Lett, 458, 175-179. Impact factor: 3.58; citation :34
  • Bera A.K. Ghosh S and Das S (1995) Mitochondrial VDAC can be phosphorylated by cyclic AMP-dependent protein kinase. Biochem Biophys Res Commun,209, 213-217. Impact factor: 2.40; citation: 52

Book Chapter

  • Akabas, M.H., Horenstein, J., Williams, D.B., Bali, M., and Bera A.K.,2002. GABAA Receptors: Probing the Structural Basis of Function, Gating and Pharmacological Modulation by General Anesthetics. Molecular and Basic Mechanisms of Anesthesia.Ed. M. Barann and B.W. Urban. Pabst Science Publishers, Germany.