• The organisational structure of protein networks

    How are protein networks organised, structurally, in terms of the connectivity of essential and non-essential proteins?
    Does the centrality–lethality hypothesis hold good for different types of organisms?
    Do essential proteins hold a special position in the network organisation?
    What are the important network metrics that can decide if a protein is likely to be essential?

    Mtb_700_centrality_lethality
  • Modelling communities of micro-organisms

    How do organisms interact in communities? How do such systems respond to perturbations (like a drug, or diet)?

    3
  • BT3240: Metabolic Regulation

    How is the complex process of metabolism controlled?
    How can we manipulate microbes towards desired engineering goals?

    bt3190_wordle
  • BT5240: Computational Systems Biology

    How can we model complex biological systems at various levels? How can we represent/visualise/analyse massive biological networks? How do biological systems respond to perturbations?

    bt5240_wordle
  • CUDA Research Centre

    In July 2011, our lab was chosen by nVidia as a CUDA Research Centre.

    NV_CUDA_Research_Center_3D
  • Evolvability of programmable hardware

    Can artificial systems be designed with properties of evolvability and robustness, like biological systems?

    network_diagram

Revisiting the centrality–lethality hypothesis

Protein networks, describing physical interactions as well as functional associations between proteins, have been...

27th Aug
Mtb_700_centrality_lethality

BT 3240 – Metabolic Regulation

How is the complex process of metabolism controlled? How do organisms regulate...

15th Apr
bt3190_wordle

Modelling communities of micro-organisms

Micro-organisms are rarely found to live in isolation in their natural environment....

01st Mar
2

BT5240 – Computational Systems Biology

How can we model complex biological systems at various levels? How can...

30th Oct
bt5240_wordle

BT 3190 – Metabolic Regulation

Course contents Overview of cellular metabolism Structure and organisation of metabolic networks...

10th Apr
BT 3190 – Metabolic Regulation

CUDA Research Centre

In July 2011, our lab was chosen as a CUDA Research Centre...

21st Jul
NV_CUDA_Research_Center_3D

BT 3190 – Metabolic regulation

Course contents Overview of cellular metabolism Structure and organisation of metabolic networks...

22nd Apr
BT 3190 – Metabolic regulation

Evolvability and robustness of TOR signalling

Biological systems at various levels of organisation exhibit robustness, as well as...

11th Jan
TOR_neutral_networks

Evolvability of programmable hardware

In biological systems, individual phenotypes are typically adopted by multiple genotypes. Examples...

09th Jun
network_diagram
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