Genome-scale metabolic model led engineering of Nothapodytes nimmoniana plant cells for high camptothecin production
Camptothecin (CPT) is a vital monoterpene indole alkaloid used in anti-cancer therapeutics....
Computational Systems Biology Lab
Karthik Raman's Lab @ IIT Madras
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A Computational Framework to Identify Metabolic Engineering Strategies for the Co-Production of Metabolites
Microbial production of chemicals is a more sustainable alternative to traditional chemical...
Deciphering the metabolic capabilities of Bifidobacteria using genome-scale metabolic models
Bifidobacteria, the initial colonisers of breastfed infant guts, are considered as the...
Rational metabolic engineering for enhanced alpha-tocopherol production in Helianthus annuus cell culture
Alpha-tocopherol, an essential dietary supplement, synthesized by photosynthetic organisms is the most...
Uncovering Novel Pathways for Enhancing Hyaluronan Synthesis in Recombinant Lactococcus lactis: Genome-Scale Metabolic Modeling and Experimental Validation
Hyaluronan (HA), a glycosaminoglycan with important medical applications, is commercially produced from...
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