Publications

Yadav A, Sinha H* (2016) Gene-gene and gene environment interactions in complex traits in yeast. Yeast (invited review)

Sarkar C, Gupta S, Sinha H*, Jalan S* (2016) A network theory approach identifies nodes and edges defining yeast sporulation efficiency variation. bioRxiv doi: 10.1101/068270 [PDF]

Yadav A, Dhole K, Sinha H* (2016) Differential regulation of cryptic genetic variation shapes the genetic interactome underlying complex traits. Genome Biology and Evolution 8: 3559 [PDF]PMID: in process

Yadav A, Radhakrishnan A, Panda A, Singh A, Sinha H*, Bhanot G* (2016) The modular adaptive ribosome. PLOS ONE 11: e0166021 [PDF] PMID: 27812193

Yadav A*, Dhole K, Sinha H* (2016) Genetic regulation of phenotypic plasticity and canalisation in yeast growth. PLOS ONE 11: e0162326 [PDF] PMID: 27611930

Gupta S, Radhakrishnan A, Nitin R, Pandu R-L, Lin G, Steinmetz LM, Gagneur J, Sinha H* (2016) Meiotic interactors of a mitotic gene TAO3 revealed by functional analysis of its rare variant. G3: Genes, Genomics, Genetics 6: 2255 [PDF] PMID: 27317780

Gupta S, Radhakrishnan A, Pandu R-L, Lin G, Steinmetz LM, Gagneur J, Sinha H* (2015) Temporal expression profiling identifies pathways mediating effect of causal variant on phenotype. PLOS Genetics 11: e1005195 [PDF] PMID: 26039065

Yadav A, Radhakrishnan A, Bhanot G, Sinha H* (2015) Differential regulation of antagonistic pleiotropy in synthetic and natural populations suggests its role in adaptation. G3: Genes, Genomics, Genetics 5: 699 [PDF] PMID: 25711830

Singh R, Sinha H* (2015) Tiled ChrI RHS collection: a pilot high-throughput screening tool for identification of allelic variants. Yeast 32: 335 [PDF] PMID: 25407353

Tomar P, Sinha H* (2014) Conservation of PHO pathway in yeasts and role of Pho84. Journal of Biosciences 39: 1 [PDF] PMID: 24845516

Bhatia A, Yadav A, Zhu C, Gagneur J, Steinmetz LM, Bhanot G, Sinha H* (2014) Yeast growth plasticity is regulated by environment specific multi-QTL interactions. G3: Genes, Genomes, Genetics 4: 769 [PDF] PMID: 24474169

Tomar P, Bhatia A, Ramdas S, Diao L, Bhanot G, Sinha H* (2013) Sporulation genes associated with sporulation efficiency in natural isolates of yeast. PLOS ONE 8: e69765 [PDF] PMID: 23874994

Fraser HB, Levy S, Chavan A, Shah HB, Perez JC, Zhou Y, Siegal ML, Sinha H (2012) Polygenic cis-regulatory adaptation in the evolution of yeast pathogenicity. Genome Research 22: 1930 [PDF] PMID: 22645260

Gagnuer J, Sinha H, Perocchi F, Bourgon R, Huber W, Steinmetz LM (2009) Genome-wide allele- and strand-specific expression profiling. Molecular Systems Biology 5: 274 [PDF] PMID: 19536197

Sinha H, David L, Pascon RC, Clauder-Münster S, Krishnakumar S, Nguyen M, Shi G, Dean J, Davis RW, Oefner PJ, McCusker JH, Steinmetz LM (2008) Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast. Genetics 180: 1661 [PDF] PMID: 18780730

Sinha H, Nicholson BP, Steinmetz LM, McCusker JH (2006) Complex genetic interactions in a quantitative trait locus. PLOS Genetics 2: e13 [PDF] PMID: 16462944

Ito-Harashima S, Hartzog PE, Sinha H, McCusker JH (2002) The tRNA-Tyr gene family of Saccharomyces cerevisiae: agents of phenotypic variation and position effects on mutation frequency. Genetics 161: 1395 [PDF] PMID: 12196388

Steinmetz LM, Sinha H, Richards DR, Spiegelman JI, Oefner PJ, McCusker JH, Davis RW (2002) Dissecting the architecture of a quantitative trait locus in yeast. Nature 416: 326 [PDF] PMID: 11907579

Sinha H, Pain A, Johnstone K (2000) Analysis of the role of recA in phenotypic switching of Pseudomonas tolaasii. Journal of Bacteriology 182: 6532 [PDF] PMID: 11053404

Singh G, Sinha H, Ashby AM (2000) Cloning and expression studies during vegetative and sexual development of Pbs1, a septin gene homologue from Pyrenopeziza brassicae. Biochimica Biophysica Acta: Molecular Cell Research 1497: 168 [PDF] PMID: 10838170