Publications

  1. Venkatesan N, Xavier A, Sindhu KJ, Sinha H*, Devrajan K (2021) Identification and validation of putative target genes regulated by miR-34 in cervical cancer. bioRxiv 
  2. Vijayram R, Damaraju N, Xavier A, Desiraju BK, Thiruvengadam R, Misra S, Chopra S, Khurana A, Wadhwa N, Garbh-Ini Study Group, Rengaswamy R, Sinha H*, Bhatnagar S* (2021) Comparison of first trimester dating methods for gestational age estimation and their implication on preterm birth classification in a North Indian cohort. BMC Pregnancy and Childbirth 21: 343
  3. Choobdar S, Ahsen ME, Crawford J, Tomasoni M, Lamparter D, Lin J, Hescott B, Hu X, Mercer J, Natoli T, Narayan R, The DREAM Module Identification Challenge Consortium, Subramanian A, Stolovitzky G, Kutalik Z, Lage K, Slonim DK, Saez-Rodriguez J, Cowen LJ, Bergmann S, Marbach D* (2019) Open Community Challenge Reveals Molecular Network Modules with Key Roles in Diseases. Nature Methods 16: 843
  4. Tripathi B, Parthasarathy S, Sinha H, Raman K, Ravindran B* (2019) Adapting community detection algorithms for disease module identification in heterogeneous biological networks. Frontiers in Genetics 10: 164
  5. Sambamoorthy G, Sinha H*, Raman K* (2019) Evolutionary design principles in metabolism. Proceedings of the Royal Society B: Biological Sciences 286: 20190098
  6. Sarkar C, Gupta S, Sinha H*, Jalan S* (2018) A network theory approach identifies nodes and edges defining yeast sporulation efficiency variation. bioRxiv
  7. Yadav A, Sinha H* (2018) Gene-gene and gene environment interactions in complex traits in yeast. Yeast 35: 403
  8. Yadav A, Dhole K, Sinha H* (2016) Differential regulation of cryptic genetic variation shapes the genetic interactome underlying complex traits. Genome Biology and Evolution 8: 3559
  9. Yadav A, Radhakrishnan A, Panda A, Singh A, Sinha H*, Bhanot G* (2016) The modular adaptive ribosome. PLOS ONE 11: e0166021
  10. Yadav A*, Dhole K, Sinha H* (2016) Genetic regulation of phenotypic plasticity and canalisation in yeast growth. PLOS ONE 11: e0162326
  11. Gupta S, Radhakrishnan A, Nitin R, Pandu R-L, Lin G, Steinmetz LM, Gagneur J, Sinha H* (2016) Meiotic interactors of a mitotic gene TAO3 revealed by functional analysis of its rare variant. G3: Genes, Genomics, Genetics 6: 2255
  12. Gupta S, Radhakrishnan A, Pandu R-L, Lin G, Steinmetz LM, Gagneur J, Sinha H* (2015) Temporal expression profiling identifies pathways mediating effect of causal variant on phenotype. PLOS Genetics 11: e1005195
  13. Yadav A, Radhakrishnan A, Bhanot G, Sinha H* (2015) Differential regulation of antagonistic pleiotropy in synthetic and natural populations suggests its role in adaptation. G3: Genes, Genomics, Genetics 5: 699
  14. Singh R, Sinha H* (2015) Tiled ChrI RHS collection: a pilot high-throughput screening tool for identification of allelic variants. Yeast 32: 335
  15. Tomar P, Sinha H* (2014) Conservation of PHO pathway in yeasts and role of Pho84. Journal of Biosciences 39: 1
  16. Bhatia A, Yadav A, Zhu C, Gagneur J, Steinmetz LM, Bhanot G, Sinha H* (2014) Yeast growth plasticity is regulated by environment specific multi-QTL interactions. G3: Genes, Genomes, Genetics 4: 769
  17. Tomar P, Bhatia A, Ramdas S, Diao L, Bhanot G, Sinha H* (2013) Sporulation genes associated with sporulation efficiency in natural isolates of yeast. PLOS ONE 8: e69765
  18. Fraser HB, Levy S, Chavan A, Shah HB, Perez JC, Zhou Y, Siegal ML, Sinha H (2012) Polygenic cis-regulatory adaptation in the evolution of yeast pathogenicity. Genome Research 22: 1930
  19. Gagnuer J, Sinha H, Perocchi F, Bourgon R, Huber W, Steinmetz LM (2009) Genome-wide allele- and strand-specific expression profiling. Molecular Systems Biology 5: 274
  20. Sinha H, David L, Pascon RC, Clauder-M√ľnster S, Krishnakumar S, Nguyen M, Shi G, Dean J, Davis RW, Oefner PJ, McCusker JH, Steinmetz LM (2008) Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast. Genetics 180: 1661
  21. Sinha H, Nicholson BP, Steinmetz LM, McCusker JH (2006) Complex genetic interactions in a quantitative trait locus. PLOS Genetics 2: e13
  22. Ito-Harashima S, Hartzog PE, Sinha H, McCusker JH (2002) The tRNA-Tyr gene family of Saccharomyces cerevisiae: agents of phenotypic variation and position effects on mutation frequency. Genetics 161: 1395
  23. Steinmetz LM, Sinha H, Richards DR, Spiegelman JI, Oefner PJ, McCusker JH, Davis RW (2002) Dissecting the architecture of a quantitative trait locus in yeast. Nature 416: 326
  24. Sinha H, Pain A, Johnstone K (2000) Analysis of the role of recA in phenotypic switching of Pseudomonas tolaasii. Journal of Bacteriology 182: 6532
  25. Singh G, Sinha H, Ashby AM (2000) Cloning and expression studies during vegetative and sexual development of Pbs1, a septin gene homologue from Pyrenopeziza brassicae. Biochimica Biophysica Acta: Molecular Cell Research 1497: 168