Publications

  1. Choobdar S, Ahsen ME, Crawford J, Tomasoni M, Lamparter D, Lin J, Hescott B, Hu X, Mercer J, Natoli T, Narayan R, The DREAM Module Identification Challenge Consortium, Subramanian A, Stolovitzky G, Kutalik Z, Lage K, Slonim DK, Saez-Rodriguez J, Cowen LJ, Bergmann S, Marbach D* (2018) Open Community Challenge Reveals Molecular Network Modules with Key Roles in Diseases. bioRxiv
  2. Sarkar C, Gupta S, Sinha H*, Jalan S* (2018) A network theory approach identifies nodes and edges defining yeast sporulation efficiency variation. bioRxiv
  3. Yadav A, Sinha H* (2018) Gene-gene and gene environment interactions in complex traits in yeast. Yeast 35: 403
  4. Yadav A, Dhole K, Sinha H* (2016) Differential regulation of cryptic genetic variation shapes the genetic interactome underlying complex traits. Genome Biology and Evolution 8: 3559
  5. Yadav A, Radhakrishnan A, Panda A, Singh A, Sinha H*, Bhanot G* (2016) The modular adaptive ribosome. PLOS ONE 11: e0166021
  6. Yadav A*, Dhole K, Sinha H* (2016) Genetic regulation of phenotypic plasticity and canalisation in yeast growth. PLOS ONE 11: e0162326
  7. Gupta S, Radhakrishnan A, Nitin R, Pandu R-L, Lin G, Steinmetz LM, Gagneur J, Sinha H* (2016) Meiotic interactors of a mitotic gene TAO3 revealed by functional analysis of its rare variant. G3: Genes, Genomics, Genetics 6: 2255
  8. Gupta S, Radhakrishnan A, Pandu R-L, Lin G, Steinmetz LM, Gagneur J, Sinha H* (2015) Temporal expression profiling identifies pathways mediating effect of causal variant on phenotype. PLOS Genetics 11: e1005195
  9. Yadav A, Radhakrishnan A, Bhanot G, Sinha H* (2015) Differential regulation of antagonistic pleiotropy in synthetic and natural populations suggests its role in adaptation. G3: Genes, Genomics, Genetics 5: 699
  10. Singh R, Sinha H* (2015) Tiled ChrI RHS collection: a pilot high-throughput screening tool for identification of allelic variants. Yeast 32: 335
  11. Tomar P, Sinha H* (2014) Conservation of PHO pathway in yeasts and role of Pho84. Journal of Biosciences 39: 1
  12. Bhatia A, Yadav A, Zhu C, Gagneur J, Steinmetz LM, Bhanot G, Sinha H* (2014) Yeast growth plasticity is regulated by environment specific multi-QTL interactions. G3: Genes, Genomes, Genetics 4: 769
  13. Tomar P, Bhatia A, Ramdas S, Diao L, Bhanot G, Sinha H* (2013) Sporulation genes associated with sporulation efficiency in natural isolates of yeast. PLOS ONE 8: e69765
  14. Fraser HB, Levy S, Chavan A, Shah HB, Perez JC, Zhou Y, Siegal ML, Sinha H (2012) Polygenic cis-regulatory adaptation in the evolution of yeast pathogenicity. Genome Research 22: 1930
  15. Gagnuer J, Sinha H, Perocchi F, Bourgon R, Huber W, Steinmetz LM (2009) Genome-wide allele- and strand-specific expression profiling. Molecular Systems Biology 5: 274
  16. Sinha H, David L, Pascon RC, Clauder-M√ľnster S, Krishnakumar S, Nguyen M, Shi G, Dean J, Davis RW, Oefner PJ, McCusker JH, Steinmetz LM (2008) Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast. Genetics 180: 1661
  17. Sinha H, Nicholson BP, Steinmetz LM, McCusker JH (2006) Complex genetic interactions in a quantitative trait locus. PLOS Genetics 2: e13
  18. Ito-Harashima S, Hartzog PE, Sinha H, McCusker JH (2002) The tRNA-Tyr gene family of Saccharomyces cerevisiae: agents of phenotypic variation and position effects on mutation frequency. Genetics 161: 1395
  19. Steinmetz LM, Sinha H, Richards DR, Spiegelman JI, Oefner PJ, McCusker JH, Davis RW (2002) Dissecting the architecture of a quantitative trait locus in yeast. Nature 416: 326
  20. Sinha H, Pain A, Johnstone K (2000) Analysis of the role of recA in phenotypic switching of Pseudomonas tolaasii. Journal of Bacteriology 182: 6532
  21. Singh G, Sinha H, Ashby AM (2000) Cloning and expression studies during vegetative and sexual development of Pbs1, a septin gene homologue from Pyrenopeziza brassicae. Biochimica Biophysica Acta: Molecular Cell Research 1497: 168