Elucidating the biosynthetic pathways of volatile organic compounds in Mycobacterium tuberculosis through a computational approach
Microbial volatile organic compounds (VOCs) have gained prominence in the recent past...
Computational Systems Biology Lab
Karthik Raman's Lab @ IIT Madras
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A General Mechanism for the Propagation of Mutational Effects in Proteins
Mutations in the hydrophobic interior of proteins are generally thought to weaken...
In Silico Approaches to Metabolic Engineering
With an increasing understanding of the cell at the molecular level, primarily...
Critical assessment of genome-scale metabolic networks: the need for a unified standard
Genome-scale metabolic networks have been reconstructed for several organisms. These metabolic networks...
Revisiting Robustness and Evolvability: Evolution in Weighted Genotype Spaces
Robustness and evolvability are highly intertwined properties of biological systems. The relationship...
Fast-SL: An efficient algorithm to identify synthetic lethals
Synthetic lethal sets are sets of reactions/genes where only the simultaneous removal...
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