Understanding the evolution of functional redundancy in metabolic networks
Metabolic networks are highly robust to perturbations by employing redundant genes or...
Computational Systems Biology Lab
Karthik Raman's Lab @ IIT Madras
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Predicting Novel Metabolic Pathways through Subgraph Mining
Motivation: The ability to predict pathways for biosynthesis of metabolites is very...
Elucidating the biosynthetic pathways of volatile organic compounds in Mycobacterium tuberculosis through a computational approach
Microbial volatile organic compounds (VOCs) have gained prominence in the recent past...
A General Mechanism for the Propagation of Mutational Effects in Proteins
Mutations in the hydrophobic interior of proteins are generally thought to weaken...
In Silico Approaches to Metabolic Engineering
With an increasing understanding of the cell at the molecular level, primarily...
Critical assessment of genome-scale metabolic networks: the need for a unified standard
Genome-scale metabolic networks have been reconstructed for several organisms. These metabolic networks...
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