Computational Systems Biology Lab

An Introduction to Computational Systems Biology

The textbook is now available! “An Introduction to Computational Systems Biology: Systems-Level Modelling of Cellular Networks” (by CRC Press)
CASTLE: Computational Analysis of SynThetic LEthals

Access the CASTLE database at: https://ramanlab.github.io/CASTLE/
NetGenes: Interactions Networks to Gene Essentiality

Gene essentiality predictions for 2700+ organisms based on their interactomes!
MinReact: a systematic approach for identifying minimal metabolic networks

Our latest method for identifying minimal networks, published in Bioinformatics
Investigating metabolic interactions in a microbial co-culture through integrated modelling and experiments

A unique blend of theory and experiments to understand metabolic interactions in a co-culture.
Deciphering the metabolic capabilities of Bifidobacteria using genome-scale metabolic models

A multi-pronged modelling approach to systematically characterise bifidobacteria based on their various phenotypic and metabolic features under different nutritional environments
NPTEL MOOC on Computational Systems Biology
Understanding the evolution of functional redundancy in metabolic networks

How do reactions compensate for one another in metabolic networks?

Adapting Community Detection Algorithms for Disease Module Identification in Heterogeneous Biological Networks

Biological networks catalog the complex web of interactions happening between different molecules,...

14th Feb

Adapting Community Detection Algorithms for Disease Module Identification in Heterogeneous Biological Networks

Evolutionary design principles in metabolism

Microorganisms are ubiquitous and adapt to various dynamic environments to sustain growth....

11th Feb

Evolutionary design principles in metabolism

Network-based features enable prediction of essential genes across diverse organisms

Machine learning approaches to predict essential genes have gained a lot of...

04th Dec

Network-based features enable prediction of essential genes across diverse organisms

Metabolite systems profiling identifies exploitable weaknesses in retinoblastoma

Retinoblastoma (RB) is a childhood eye cancer. Currently, chemotherapy, local therapy, and...

10th Nov

DBT-funded JRF position

Open Position Applications are invited for a Junior Research Fellow (JRF) position...

15th Oct

Systems-Level Modelling of Microbial Communities: Theory and Practice

Systems-Level Modelling of Microbial Communities: Theory and Practice introduces various aspects of...

24th Sep

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