Computational Systems Biology Lab

An Introduction to Computational Systems Biology

The textbook is now available! “An Introduction to Computational Systems Biology: Systems-Level Modelling of Cellular Networks” (by CRC Press)

CASTLE: Computational Analysis of SynThetic LEthals

Access the CASTLE database at: https://ramanlab.github.io/CASTLE/

NetGenes: Interactions Networks to Gene Essentiality

Gene essentiality predictions for 2700+ organisms based on their interactomes!

MinReact: a systematic approach for identifying minimal metabolic networks

Our latest method for identifying minimal networks, published in Bioinformatics

Investigating metabolic interactions in a microbial co-culture through integrated modelling and experiments

A unique blend of theory and experiments to understand metabolic interactions in a co-culture.

Deciphering the metabolic capabilities of Bifidobacteria using genome-scale metabolic models

A multi-pronged modelling approach to systematically characterise bifidobacteria based on their various phenotypic and metabolic features under different nutritional environments

NPTEL MOOC on Computational Systems Biology

Understanding the evolution of functional redundancy in metabolic networks

How do reactions compensate for one another in metabolic networks?